Scientist - Bioassay Development - Immuno/Oncology

Location
Tarrytown, New York
Salary
Competitive salary and benefits
Posted
May 16, 2018
Closes
Jul 14, 2018
Ref
12860BR
Education
PHD
Career Fair Category
Career Fair

Scientist - Bioassay Development - Immuno/Oncology

Position Summary

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary
Are you the SCIENTIST we are looking for to join our dynamic Immuno-Oncology (I/O) bioassay team? Would you love to work in a highly innovative, inspiring environment - with unlimited resources of state of the art technologies? Do you love to collaborate within and outside your team? If yes, don’t waste your time. You have found your destiny. Our group works on the development of highly complex bioassays for I/O. Bioassays we develop, are employed for the screening of fully-human antibodies generated in our proprietary VelocImmuneTM mice. In cross-departmental meetings, we present and discuss our findings to our strong scientifically-driven senior leaders to move therapeutic drugs into clinic. What we really like about our bioassay team, is the energizing environment which drives us constantly to come up with better approaches and concepts. Therefore, your passion, your enthusiasm, your scientific curiosity to create challenging bioassays is needed to find new therapeutic drugs. In order to be able to match you with our team, you’ll need following requirements and you’ll have following responsibilities:

Responsibilities
1) Isolate/process immune cells from human blood samples
2) Develop human primary cell-based functional assays
3) Develop cell-based functional assays using engineered-immortalized cells
4) Mammalian cell culture of adherent and non-adherent cell lines

5) Operate a variety of instruments including but not limited to HyperCyte, Accuri C6 cytometer, Cytoflex, ImageXpress micro XL, Victor, Hamilton, Envision Multilabel plate reader, Cell Harvester

6) Set up and run bioassays for screening and potency measurements

7) Provide Weekly presentations/verbal updates

8) Keep abreast of current/relevant literature in order to further develop scientific expertise and expand scientific/technical knowledge and skill sets
9) Train, direct and oversee the experimentation of research assistants



Requirements:
This position requires a PhD with a minimum of 2+ years related post doc experience. Ideal candidate experience will include:
1) Extensive knowledge and background in immunology
2) Expertise in handling/processing human blood samples
3) Proficient in immunofluorescence staining procedures and flow cytometry
4) Experience in primary cell activation/proliferation assays
5) Strong aseptic cell culture skills
6) Stable cell line engineering skills
7) Cell-based potency assays

Level will be commensurate with experience


To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.