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Associate Director/Director, Pathology

Employer
Seagen
Location
Bothell, Washington State
Salary
Market Rate
Closing date
Jun 30, 2019

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Job Details

Summary: 

We are seeking an experienced anatomic pathologist with exceptional scientific curiosity, critical thinking, and self-motivation to join our team of nonclinical scientists. You will be part of a vibrant and skilled group leading the scientific understanding of the safety of novel therapeutics in a company dedicated to finding cures to cancer.  Interpretation, integration, and assessment of significance of data in the context of multiple other scientific investigators both internally and externally are critical. You will be expected to review findings from nonclinical studies in support of clinical development and will have significant autonomy to propose and drive the investigative and mechanistic understanding of these toxicities. Your communication skills at all levels of interaction must be excellent. This is a pivotal role in the department reporting to the Executive Director of Nonclinical Sciences and you will be expected to contribute significantly to growing the pathology expertise within the department. In addition, you will serve as a nonclinical representative on project teams and may have opportunity to serve as a program lead on early projects.

 

Responsibilities: 

  • Foster continued development of the group’s regulatory pathology expertise through primary data generation on non-GLP and GLP studies, and peer review of external GLP studies
  • Assist in developing and delivering an overarching strategy for the delivery of anatomic pathology data, which may include internal resources and/or external partners
  • Provide internal expertise to understand the mechanisms of toxicity observed nonclinically and/or clinically in order to drive mitigation and/or back-up strategies to minimize potential harm to patients
  • Present data and interpretations in written and oral form to regulatory bodies to enable optimal clinical development and registration of novel drugs
  • Build collaborative networks internal and external to the company to ensure rapid communication and cross-functional evaluation and investigation of emerging safety issues
  • Aid in the development of a forward facing vision of the non-clinical sciences department, and support implementation of this vision
  • Act as a nonclinical team representative responsible for the non-clinical safety strategy of novel target/therapeutic candidates. Your ability to understand the toxicity of the platform versus target related toxicities is key
  • Develop strong knowledge of the basic biology of the intended target of drug candidates
  • Represent Seattle Genetics in the external scientific environment – influencing partners and regulators in a positive way  


Qualifications:

  • 10 to 12 years of toxicologic pathology experience in a contract research organization and/or pharmaceutical/biotech setting, reading slides, interpreting data, generating reports and regulatory documents
  • Experience in nonclinical safety assessment from discovery through development, especially with biologics
  • Proven success in scientific investigation of fundamental pathology issues, either through scientific publications or drug development experience


Education:

  • D.V.M. (or equivalent)
  • Ph.D. in toxicology, pathology, comparative biology, or a related field
  • Diplomate, American College of Veterinary Pathologists (or equivalent) in anatomic pathology

As the leading employer in our industry in the Pacific Northwest, Seattle Genetics is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seattle Genetics, please visit www.seattlegenetics.com.


Seattle Genetics is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law. 

Company

Seagen is a global biotechnology company that develops and commercializes transformative cancer therapies. We’re driven by a singular mission—to make a difference for people impacted by cancer.

As an industry leader in antibody–drug conjugate (ADC) technology, we pioneered the science of harnessing antibodies designed to deliver cell-killing agents to cancer cells. Three of our four approved medicines are built on this technology.

We also focus our research efforts on novel targeted small molecule therapies. In addition, we are leveraging our expertise in empowered antibodies to build a portfolio of proprietary immuno-oncology agents.

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