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Sr Medical Director, Cell Therapy, Global Development

Gaithersburg, MD, NYC, Boston or Cambridge, UK
Competitive Salary and Benefits
Closing date
Jul 2, 2022
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Job Details

Senior Medical Director Cell Therapy, Global Development, Oncology R&D

Locations: Gaithersburg, Waltham, NYC, US or Cambridge, UK

Do you have expertise in, and passion for clinical development? Are you looking to work at the cutting-edge, where scientific innovations and an entrepreneurial spirit are the norm? Join the team at the heart of AstraZeneca Oncology R&D which is committed and encouraged to follow the science.

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.

Oncology Research & Development

Join the team dedicated to Cell Therapy in Oncology R&D, with an ambition to eliminate cancer as a cause of death. It’s our big vision that unites and inspires us.

With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Fusing ground breaking science with the latest technology to achieve breakthroughs. Backed by investment, we thrive to deliver 6 new molecular entities by 2025.

A place built on courage, curiosity and collaboration – we make ambitious decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team.

One area of significant investment is to build internal infrastructure to be a leader in next generation cellular therapy products in Oncology R&D. Using historical expertise in biologics engineering, gene editing and immune expertise across solid and hematological malignancies, AstraZeneca is uniquely positioned to develop the best technologies for cellular therapies and is already growing a differentiated pipeline. Backed by senior leadership, the newly formed Oncology Cell Unit will utilize the best expertise within AstraZeneca while allowing for the rapid expansion of cellular therapy research and development.

Join us and be part of building an innovative pipeline and deliver potentially high impact treatments to patients.

Position Summary:

We are seeking a well-trained Senior Medical Director, a clinician with strong leadership skills who is driven by science and the desire to develop novel Cell Therapies for cancer patients, and has a proficiency in the drug development process (especially early phase clinical trials), protocol writing & study conduct, data review and reconciliation, the principles of translational medicine, and what it takes to lead teams successfully. This individual will have the opportunity for growth and development while working in a vibrant environment.


  • Medical degree (U.S. or international equivalent) with training in Oncology, Hematology or Hem/Onc with a Board Certification or a PhD degree preferred in immunology or cell biology.
  • 3-5 years of early drug development industry experience, preferentially in the field of immuno-oncology (I/O) or cell therapy.
  • Keen interest in science and data-driven approaches to implement adaptive clinical trial designs and use pharmacometric modeling to inform dose level decisions in cell therapy dose finding studies.

The ideal candidate is encouraged to support cross-functional, matrix-based cell therapy teams on the program and study level, provide clinical expertise to devise a clinical development strategy of a given cell therapy product spanning from First-in-Human to registration, and collaborate with other departments such as clinical pharmacology, regulatory, and commercial to drive early development decisions.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Find out more:

At AstraZeneca you’ll have the chance to create a substantial difference to patients’ lives. With science at its heart, this is the place where breakthroughs born in the lab become transformative medicines – for the world’s most complex diseases. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and crafting the patient ecosystem.

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