Physician-Scientist Early Investigator Program

National Cancer Institute, Center for Cancer Research
Bethesda, Maryland
Competitive salary commensurate with subspecialty training and experience.
Closing date
Oct 10, 2022

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Clinical Research Oncology

Physician-Scientist Early Investigator Program  

The Center for Cancer Research (CCR), a division of the National Cancer Institute (NCI), National Institutes of Health (NIH), announces its annual call for applications for the Physician-Scientist Early Investigator Program (PEIP), an exciting opportunity for early career physicians dedicated to laboratory bench-to-bedside, health disparities, or clinic-based research.  NCI’s largest intramural program offers an unparalleled opportunity to build an independent clinical research program with access to plentiful beds at the world’s largest dedicated research hospital and an extensive clinical infrastructure including protocol and regulatory support, nursing, data management, information technology, shared research resources, and a broad range of scientific and clinical expertise.

Come join a vibrant, multidisciplinary research community featuring flexible funding that supports innovative, high-impact bench-to-bedside research. The PEIP assists board-eligible/board-certified translational researchers transition from a mentored position to that of an independent investigator in research, academia, or comparable positions in government and industry. Potential areas of interest include health disparities, medical oncology, pediatric hematology-oncology, radiation oncology, surgical oncology, pathology, neuro-oncology, urology, myeloid malignancies, and epidemiology and genetics. Program objectives are to: develop competence and skills in study design, protocol development and patient-oriented research; acquire knowledge related to the ethical and regulatory issues of conducting clinical research involving human subjects; gain direct experience with the collection and management of research data; and, learn about function, development, organization and leadership of a multidisciplinary clinical research team.

Who We Are
The Center for Cancer Research is the largest division of the National Cancer Institute’s intramural research program and home to nearly 250 research groups led by an extraordinary group of scientists and clinicians exploring the cutting-edge of cancer and HIV/AIDS research.  Our scientists enjoy complete intellectual freedom and are expected to explore the most important questions creatively and innovatively in the field of cancer research and treatment. We support projects over a long-time horizon allowing our investigators to pursue some of the most difficult, high-risk problems in the field and the most pressing problems in modern cancer research. CCR is located on two campuses just outside of Washington, D.C in Bethesda and Frederick, Maryland.  CCR’s clinical program is housed at the NIH Clinical Center—the world’s largest hospital dedicated to clinical research.  For more information about CCR and its programs, visit   

About the Program 
Selectees will be appointed for a three-year period at a competitive salary commensurate with subspecialty training and experience. They will be assigned dedicated space, provided with an independent budget including travel and training funds, and given access to an extensive infrastructure including research nursing, data-management support, animal facilities, core services and advanced technologies such as imaging/microscopy, protein chemistry and purification, mass spectrometry, flow cytometry, genomics and transgenic and knockout mice. An attractive Federal Government employee benefits package includes health and life insurance coverage, a retirement savings program and relocation expenses. Student loan repayment is possible through the NIH.  Program participants must develop a research proposal within the first six months in collaboration with a mentor and complete courses focused on leadership/management skills and writing cancer grant applications. Research progress will be reviewed on an annual basis.  For more information on the PEIP, visit

Candidates may be U.S. citizens, permanent residents, or possess (or be eligible for) an appropriate work visa.  Candidates must hold an M.D. degree (or equivalent) and must have successfully completed subspecialty training at a U.S. accredited institution in an appropriate field.

A degree from a foreign medical school must provide education and medical knowledge equivalent to accredited schools in the United States.  Evidence of equivalency to accredited schools in the United States is demonstrated by permanent certification by the Educational Commission for Foreign Medical Graduates (ECFMG), a fifth pathway certificate for Americans who completed premedical education in the United States and graduate education in a foreign country, or successful completion of the U.S. Medical Licensing Examination.

Applicants must possess a current, active, full and unrestricted license or registration as a Physician from a State, the District of Columbia, the Commonwealth of Puerto Rico, or a territory of the United States. Foreign physicians on an NIH-sponsored work visa are exempt from the licensure requirement.

How to Apply
Applicants must submit a current curriculum vitae with bibliography, contact information for three letters of recommendation, and a description of research interests and goals and as they relate to the chosen field (2-4 pages).  Applicants must also submit a diversity statement describing their track record of and commitment to promoting diversity, equity, and inclusion in biomedical research and/or medicine (500 word limit), including but not limited to successful recruitment and/or mentorship of trainees from historically underrepresented groups, participation on committees and in program /initiatives addressing issues of diversity and inclusion, and future plans for addressing diversity and inclusion as a principal investigator.

Apply online at  Applications will be accepted on a rolling basis. Paper or e-mailed applications will not be accepted.  Questions may be directed to: 

DHHS, NIH, and NCI are Equal Opportunity Employers

The NCI and the CCR are deeply committed to diversity of thought, equity and inclusion and encourages applications from qualified women, under-represented minorities, and individuals with disabilities.

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