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Head of Clinical Research

Employer
Chordoma Foundation
Location
Remote
Salary
Commensurate with experience
Closing date
Dec 17, 2022

Fifteen years of research investment by the Chordoma Foundation has yielded a growing pipeline of promising systemic therapy concepts, spanning new drug development, repositioning and repurposing. As these concepts advance and the therapeutic pipeline continues to grow, there is an increasing need for the Foundation to play a more active role in driving clinical research. Our new Head of Clinical Research will lead that critical aspect of our research mission.

The primary aims of this role are to:

  • Accelerate clinical evaluation of new therapeutic concepts
  • Deepen understanding of the natural history of the disease
  • Generate evidence needed to enable better, more personalized care

In this position, you will be responsible for shaping our clinical research strategy, overseeing our clinical research-enabling programs, and managing and initiating relationships with various stakeholders and partners. You will advance research both by supporting the work of academic investigators and companies, and – akin to a virtual biotech – by directing your own research, leveraging the Foundation’s own data and broad patient network. Your work will take place within a nimble and supportive work environment and within a collaborative, constructive and mission-oriented research community focused on improving the lives of patients.

POSITION OVERVIEW

  • New full-time position, reports to the Executive Director
  • Fully remote, open to candidates located anywhere in the U.S.
  • Travel required to Foundation events and research conferences

RESPONSIBILITIES

  • Therapy evaluation
  • Work with internal and external partners to identify, vet and shape promising trial concepts
  • Engage the chordoma patient community in our trial strategy and drive their participation
  • Develop strategies and programs to increase the speed, efficiency and impact of investigator-initiated and industry-sponsored trials
  • Oversee and monitor progress of supported studies
  • Lead development and adoption of chordoma-relevant trial endpoints
  • Natural history and observational research
  • Define and prioritize clinical research questions
  • Manage partnerships with various investigator-led observational studies including ongoing studies through NCI and others
  • Design and implement a clinical data registry(ies) to support natural history research, leveraging the Foundation’s broad patient and provider networks
  • Facilitate biospecimen acquisition and clinical data collection and structuring, and promote accrual through direct patient participation and partnerships with high-volume treatment centers
  • Healthcare improvement
  • Support development and/or updates of treatment guidelines
  • Facilitate dissemination of new clinically relevant evidence to treating physicians
  • Strategy, relationships and revenue
  • Develop and leverage relationships with key internal (e.g., our Medical Advisory and Community Advisory Boards) and external (e.g., clinical researchers, leading healthcare providers, relevant funders, etc.) stakeholders
  • Convene and connect clinical research stakeholders including by hosting research roundtables and co-organizing the Foundation’s biannual research workshops
  • Guide clinical development strategy of companies working to develop or reposition drugs for chordoma
  • Pursue funding for the Foundation’s clinical research priorities from industry partners, government funding agencies and foundations; partner with our Development team on fundraising from individual donors

QUALIFICATIONS

  • Doctoral degree (PhD, MD or PharmD)
  • At least five years of professional experience in oncology clinical development
  • Familiarity with the cancer therapy and drug development landscape
  • Excellent ability to manage relationships, influence various stakeholders, and coordinate with partners to achieve specific objectives
  • Strong data management skills, including a working knowledge of common clinical data ontologies, and best practices for structuring and storage of clinical data
  • Experience supervising contractors/vendors, ensuring high productivity and quality work
  • Highly organized and able to successfully advance multiple projects in parallel
  • An optimistic outlook and an entrepreneurial approach, with the ability to conceive of and implement new solutions or programs as needed
  • Excellent written and verbal communication skills, including a strong ability to translate scientific concepts into terms understandable to business and lay audiences
  • Strong inclination to use technology to maximize efficiency

COMPENSATION AND BENEFITS

The Chordoma Foundation offers a competitive salary and benefits package including:

  • 100% employer-sponsored health insurance plan
  • Dental and vision insurance
  • Short and long-term disability insurance
  • Life insurance
  • SIMPLE IRA with company matching
  • Holidays and paid time off 

Other perks of this job include:

  • Substantial schedule flexibility
  • Significant visibility and network-building opportunities with premier scientists, companies and investors
  • Support for professional development, learning and skills building
  • Highly nimble, efficient and tech-enabled work environment
  • Opportunities to initiate, build and own new programs, projects and alliances
  • Personal connection with the patients and families whose lives your work will touch

Please apply here: https://forms.clickup.com/2355454/f/27w7y-10867/6J3O7PMI63FF4ZUXLB

ABOUT THE CHORDOMA FOUNDATION

The Chordoma Foundation is a nonprofit organization created by patients and families to be an agent of change on behalf of those affected by chordoma – a rare bone cancer of the skull and spine. We envision a future in which everyone diagnosed with chordoma is able to overcome their disease and maintain their quality of life. To realize this vision, we help patients and families dealing with chordoma take on their disease, armed with information from the world’s leading medical experts as well as support from a community of peers. At the same time, we help doctors, researchers, and companies work together to accelerate the development of better treatments for the disease. Since 2007, our work has enabled thousands of patients to get the care they need, produced the first published treatment guidelines for chordoma, and advanced research that has resulted in seven new clinical trials. Now, with a motivated community of patients, doctors, and researchers, and new, even more powerful drugs in development, we are on the cusp of changing the outlook for individuals with this disease. We are looking for passionate and entrepreneurial professionals to join us in this quest.

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