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Research Scientist, Drs Owen O'Connor and Enrica Marchi Lab

University of Virginia
Charlottesville, Virginia
Closing date
Dec 28, 2022

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Research Associate

The University of Virginia Comprehensive Cancer Center seeks a Research Scientist with expertise in basic cancer immunology to understand the immunomodulatory effects of drugs on the immune microenvironment, with an emphasis on understanding how epigenetic drugs modulate the immune microenvironment.   


Qualified candidates must have at least a Ph.D. with at least 2 years of laboratory experience or M.D. with a minimum of 3 years of laboratory experience.  In addition to being skilled in routine cell culture, the appropriate candidate should be familiar or directly experienced with the following techniques: methods to generate antibodies; antibody isolation and purification, ELISA, ELISPOT, flow cytometry, immunoblotting, immunohistochemistry, immunoprecipitation and immune cell isolation.  A familiarity with gene expression array and gene set enrichment analysis would be considered an advantage, as would 3D cell culture methods.  Similarly, the candidate should have some experience conducting experiments in small animal (murine) models. 

The candidate will contribute to developing research grant proposals and may pursue independent research funding that complements ongoing research. They will be fully integrated into a well-funded (R01, American Cancer Society Research support, major funding through the Translational Orphan Blood Cancer Research Initiative) world-class laboratory with over 100 years of experience conducting state-of-the-art research and drug discovery and development focused on blood cancers.  Successful candidates must have effective oral and written communication skills as evidenced by a solid track record of scientific manuscripts and presentations. Career advancement opportunities will be strongly supported, as will independent innovative research proposals. The candidate will be in a translational research laboratory and will report directly to Drs. Enrica Marchi and Owen A. O’Connor, in the Department of Medicine, Division of Hematologic Oncology.


This position is located in Charlottesville, VA.


This is a restricted position; continuation is dependent on funding and satisfactory performance.


Review of applications will begin November 10, 2022, but this position will remain open until filled.  The University will perform background checks on all new hires prior to employment.  A completed pre-employment health screen is required for this position prior to employment. 


To Apply:

Please apply through Workday, and search for R0041484.  Complete an application online with the following documents:

  • CV
  • Cover letter detailing your skillsets, educational and work experiences
  • Contact information for 3 references


Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs'.


For questions about the application process, please contact Jessica Russo, Recruiter, at


For more information about UVA and the Charlottesville community please see and





COVID Vaccination Requirement and Guidelines


Please visit the UVA COVID-19 Job Requirements and Guidelines webpage prior to applying for current information regarding vaccination requirements and guidelines for employment at UVA.




The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff.  We believe diversity is excellence expressing itself through every person's perspectives and lived experiences.  We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.

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